I get like so often in this cases many mails asking for Validation of MOXY and literature on MOXY and its use.
Simple short answer from my side followed by some more professional info and ideas.
1. MOXY is the only NIRS type Who test the way it does . It tests SmO2 ( muscle oxygenation.
Other equipments test StO2 ( Tissue oxygen saturation and so on. Different great equipment test different way but all use the same wavelength.
MOXY uses the same wavelength like all the very expensive and incredible great equipments used for research and other incredible ideas.. What we look for in practical application is :
Can we repeat the test and the information. This way we can see actual change from withing one individual person.
Comparing absolute values with different people is interesting but the main goal is to see how SmO2 can change intraindividual due to change in training stimuli ( fatigue ) recovered and so on.)
2. The question of validation is better answered by professionals working in that field.
The same holds true to the question.
How do you validate an equipment with what ? What is the golden standard.
MOXY is for what we do the golden standard.
Here an other answer.
Near Infrared Spectroscopy (NIRS)
C. Dean Kurth MD
Cincinnati Children’s Hospital
Professor of Anesthesia and Pediatrics
University of Cincinnati College of Medicine
Determination of the accuracy of the NIRS devices has been problematic. In order to determine accuracy, the device must be compared with a gold standard. Because there is no gold standard for NIRS (ie, no other device measures O2 saturation in the tissue circulation), determination of accuracy remains an estimate. There is currently one FDA approved device, made by Somanetics. Its accuracy on the FDA application was compared relative to a weighted average (SwO2) of arterial and jugular bulb O2 saturation. In adults and children, the device is not that accurate (+10-15%) on an absolute level of oxygenation (rSO2 vs SwO2), but is fairly accurate (+5%) on a change in oxygenation ( rSO2 vs SwO2). In other words, the device indicates a change in oxygenation accurately but does not indicate accurately what the oxygenation actually is.
Other devices purport greater accuracy than the Somanetics device. However, these devices are not FDA approved, not commercially available, and have not been subject to accuracy testing on large scale. Nevertheless, several of these devices have been tested in animal models and have been found to be accurate +3% on an absolute.